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Services > Cytogenomics


Conventional karyotyping allows the study and detection of numerical and structural abnormalities of chromosomes. This technique is based on the staining of condensed chromosomes to provide a photographic representation of all chromosomes. The staining targets specific chromosomal regions called cytobands. The classification and the detection of abnormalities is based on the visual inspection of these. This is a genome-wide exploration tool with limited resolution (> 5Mb).

Main applications and advantages

  • Verification of cell cultures showing unusual growth
  • Identification of the origin of a cell line
  • Track chromosomal changes
  • Check chromosomal profile at the start and at the end of an experiment
  • QC for cell biobanking
  • QC for cells used in routine
  • QC before derivation of cell lines
  • Identification and characterisation of clonal and subclonal cell populations

Starting material

Peripheral blood, cell culture, fresh or frozen tissue, bone marrow…


  • Microscopic genomic aberrations/rearrangements > 5Mb
  • Chromosomes abnormalities: aneuploidy, inversions, duplications/deletions and translocations


Slides of metaphase cells are scanned using the Metafer platform (MetaSystems). After acquisition, all metaphases are analysed on the IKAROS karyotyping station.

Doctors and scientists can help you.